So to be clear, is it 1 or 2 ‘500mg’ tablets of GDB’s Japanese Knotwood per day? Ronse Decr., Pleuropterus zuccarinii (Small) Small, Polygonum cuspidatum Siebold & Zucc. Cat’s Claw – 7000 mg per day = 10 capsules. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Yes, there are Herxheimer reactions when treating Lyme, but don’t assume that Lyme die off is the cause of every adverse reaction. My daughter has been taking Artemisinin SOD Multi-Functional Formula by Researched Nutritionals. Japanese Knotweed- 7000mg per day = 10 capsules. Japanese Knotweed Tincture As recommended by Stephen Buhner Our very own herbal Extracts made with plants and herbs from Farmer friendly/sustainable and organic sources. This information relates to an herbal, vitamin, mineral or other dietary supplement. Pets LOVE the taste! Huzhang (Japanese Knotweed) has been used in traditional Chinese medicine as well as in Japan and Korea for many years. Because of the plant's spreading rhizomes, P. cuspidatum is grown commercially as a major source for resveratrol production (see Resveratrol monograph), while also being considered a noxious, invasive class B or C weed in certain US states.Chen 2013, Peng 2013, USDA 2013, At least 100 prescriptions using the root exist in the Pharmacopoeia of the People's Republic of China to treat bronchitis and cough, gonorrhea, inflammation, infection, jaundice, hyperlipidemia and hypertension, menopausal symptoms and amenorrhea, and skin burns. Japanese Knotweed Root is an angiogenesis modulator, stimulating the formation of new blood vessels and the healing of damaged ones in areas such as burned skin, but also stops the development of new vessels and blood flow in areas where it should not occur, … That said, I just did a quick Google search and found this article: https://www.dogsnaturallymagazine.com/natural-treatment-for-lyme-disease-in-dogs/ which says to start with 3 TBS 2x a day. Dandelion herb – 110 mg. (Taraxacum officinale) – organic – NE United States, Other ingredients: cellulose (vegetarian capsules), water, Please see these past two Q & As; Stephen does recommend the blend: http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol-2/ and http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol/. Half a gallon of fresh Japanese knotweed tincture is a perfect illustration of bioregional herbalism! . Bailey, and Reynoutria japonica Houtt. var. Each individual is unique and what works for one person may not work for another. Related. Huzhang is listed as an abortifacient in traditional Chinese medicine texts.Peng 2013. Last updated on Dec 25, 2019. Do not use if pregnant, during breastfeeding or attempting to get pregnant. I began with one herb at a time. Is this still so, or can I order from Green Dragon Botanicals? Is it really unsafe as some say? There are no clinical data regarding the use of P. cuspidatum as an antimicrobial agent. The Hawthorn’s been a God send. 1 loose tsp of this is just under 2 grams. i have 35 lb dog with lyme. Although Japanese Knotweed is edible, using its extract can be more convenient for you to use since you are getting the most of its health benefits this way. No hemolysis, agglutination reaction, or systemic anaphylaxis/skin allergy was found in tests conducted in rabbits.Peng 2013. A study among healthy volunteers found a decreased expression of modulators of inflammation in mononuclear cells following 6 weeks of P. cuspidatum extract daily containing resveratrol 40 mg.Ghanim 2010 A small study (N = 20) found decreased plasma TNF-alpha and IL-6 versus placebo.Zahedi 2013, In vitro studies have shown broad antibacterial and antifungal activity of P. cuspidatum extracts.Peng 2013, Piotrowska 2012, Song 2006 Activity against Streptococcus mutans has been investigated in oral health.Ban 2010, Pandit 2012 An ethanol extract showed inhibitory activity against HIV-1 in vitro.Lin 2010, Peng 2013. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Parenteral polydatin caused peritonitis in a subacute toxicity test in animals. Gingivitis is caused by plaque, a film of saliva and bacteria that builds up on teeth at the gum line. Sept, 2018 – am just reading Healing Lyme and ordering the core protocol herbs. Thank you. Resveratrol enhances the activity of a detoxification enzyme called CYP1A1. Required fields are marked *. Synonyms include Pleuropterus cuspidatus (Siebold & Zucc.) Your email address will not be published. Too much and you will only harm part of the plant. Once I got to the full dosage for my weight I started the next herb. For example: If the dog weighs 50 pounds, the dose would be 1/3 of what is recommended for adults. http://www.earthmedicine.ca/lyme-disease.html#Protocol, Thank you for your time today. Available for Android and iOS devices. She has been taking this dosage for two months, and is under the care of a practitioner. Cat’s Claw vine bark – 500 mg. (Uncaria tomentosa) – wildharvested – Peru . Research reveals no clinical data regarding the use of Japanese knotweed for antioxidant effect. The preparation was standardized to contain resveratrol 40 mg.Zahedi 2013, Topical application of P. cuspidatum extract has been studied in mice for anti-inflammatory effects.Bralley 2008, Wu 2012, Do not use in pregnancy. . Best, Julie. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural compound found in red grape skin, Japanese knotweed (polygonum cuspidatum), peanuts, blueberries and some other berries. The assistance of a qualified health care provider familiar with all dosage outlines, contraindications, and herb/drug interactions outlined in Healing Lyme, and familar with your personal health history and current symptoms is strongly suggested. Green Dragon’s bottle of LB Core Protocol say they base their formula on your book. Avoid use during lactation; information regarding use during lactation is lacking. http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol-2/, http://buhnerhealinglyme.com/herbs/green-dragon-botanicals-lb-core-protocol/, http://greendragonbotanicals.com/products/lyme-related-herbs/, https://www.amazon.com/dp/B015JWKYVS/ref=pd_luc_rh_sbs_01_04_t_img_lh?_encoding=UTF8&psc=1, http://biotikon.de/shop/produkt.php?aktive_nr=21, https://www.espara.com/de/produkte/detail, https://www.dogsnaturallymagazine.com/natural-treatment-for-lyme-disease-in-dogs/, Lyme disease with mycoplasma and co-infections, Instructions for wild-harvesting Japanese knotweed. https://www.amazon.com/dp/B015JWKYVS/ref=pd_luc_rh_sbs_01_04_t_img_lh?_encoding=UTF8&psc=1, Good day Mr. Stephen I want to ask how to batch resveratrol biotikon http://biotikon.de/shop/produkt.php?aktive_nr=21 and to batching andrographis paniculata espara https://www.espara.com/de/produkte/detail .asp id = 291 & tit = Andrographis% 2520Kapseln thank you. Japanese knotweed root (Polygonum cuspidatum) – • Root powder: 1 tsp – 1 TBS 3x daily. I have googled green dragon and this website has come up. Resveratrol and the whole herb support normal immune function and offer anti-inflammatory and anticancer properties. Although used for various applications, few clinical studies validate claims and guidance regarding dosing or safety is limited. If you’ve heard the old adage that wine is good for health or you are actively researching longevity, you’ve likely heard of resveratrol.. Eleutherococcus – 4200 mg per day = 6 capsules Note- I took a 2 week break every 60 days. My suspicion is that his reaction is due to these other things and has nothing to do with the Lyme. The material is intended for educational purposes only. What are your thoughts on this dosage? I have been giving it to my adult son, a lot of it…curious what he was experiencing that was so bad to stop? And after rereading your comment above, it’s possible you are simply giving him too high a dose. 3 Natural Lyme Treatments for Dogs. This is only a brief summary of general information about this product. Do you recommend this formula? Nothing in this column is intended to replace the expertise and care of a qualified health care practitioner. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. So start with 1/3 of a teaspoon and see how your dog does, then work up from there slowly. The supplement contains Artemisinin 250 mg, and Pro SOD Complex 550 mg Curcuwin Turmeric extract, Quercetin, Decaf Green Tea 95% extract, Black Walnut Hull. . The knotweed extract seems to decrease bleeding and swelling of the gums, possibly because it might interfere with the formation of plaque. The adult dosage is 1 tsp-1 TBS of the powder 3x day. Quantity – Following is a rough list for required dosages of Japanese Knotweed:- For a 150 pounds weighing adult – 1 teaspoon for 3 times in a day For a 100 pounds weighing adult – 2/3 teaspoon for 3 times in a day For 60 pounds weighing child – 1/3 teaspoons for 3 times in a day (tincture is more desirable and effective) Judy’s Herbs has the protocol in Canada in powder form. Stopped taking Turmeric/Black Pepper when starting the Hawthorn. ... Tissenbaum, H. A. Thanks so much – and thanks for all your books. Also mixing Hawthorn with Turmeric. Also taking Hawthorn capsules, 3x a day. Thank you, Kris, Any feedback on this brand of Japanese knotweed? I have the liquid tincture, Was bitten twice – 2 or 3 days ago. Mr Buhner is amazingly generous with his wisdom but there is no substitute for reading his original text, Your email address will not be published. Photo: Steve Garske. Modern preparations from Japanese Knotweed are concentrated to maximize the Resveratrol and contain very little emodin. f.) L.H. Japanese knotweed is high of vitamin A and vitamin C, that means the plant is high of antioxidants. From a more Western point of view, polygonum is high in resveratrol. LOL, I reread the reply to your comment. When taken by mouth: Knotweed is POSSIBLY SAFE when taken by mouth short-term. Learn how your comment data is processed. It is most famously known for containing high amounts of resveratrol. Due to the vitamin, It supports for the improving of the vision including protect it from several conditions such as cataract, or you can the benefits in vitamin a benefits. There are no clinical data regarding the use of P. cuspidatum in hyperlipidemia. What are the side effects of trans-veratrol? The root is used extensively in traditional medicine in China, Japan, and Korea, and the young plant parts are eaten as a vegetable. Scientific Name(s): Polygonum cuspidatum Siebold & Zucc.Common Name(s): Fleeceflower, Huzhang, Japanese bamboo, Japanese knotweed, Mexican bamboo. • Tincture: ¼ to 1 tsp 3-6x daily, OR . This plant extract exists in more than 70 plant species and is likely to be found in your environment. Is this the company you are referring to with regards to Resveratrol? Studies in rats and mice have shown antioxidant properties of P. cuspidatum that are generally attributed to the chemical constituents of resveratrol, polydatin, piceatannol, and anthraquinones and stilbenes.Kim 2010, Peng 2013, Piotrowska 2012, Zhang 2012 Carbon tetrachloride–induced liver injury and induced acute cerebral ischemia were reduced by oral extracts of P. cuspidatum.Kim 2010, Zhang 2012 In models of vascular dementia and Parkinson disease in rats, P. cuspidatum extract and polydatin administered orally resulted in improved cognitive and behavioral measures and increased antioxidant capacity in the relevant tissues.Li 2012, Wang 2011. For information specific to the activity of resveratrol, see Resveratrol. The green dragon botanical website shipping costs to canada are out of this world. And personally, even when I’m sure that what I’m having is a Herxheimer reaction, I view it as a sign that I’ve overloaded my body and I need to back off and detox. *This statement has not been evaluated by the Food and Drug Administration. Japanese knotweed contains several phytonutrients, but its medicinal properties can be primarily attributed to the substantial amount of resveratrol present in this plant. SHAKE WELL BEFORE EACH USE! & Guarente, L. Increased dosage of a sir-2 gene extends lifespan inCaenorhabditis elegans. This invasive is one of our primary defenses against Lyme infection—particularly fascinating, as knotweed thickets provide perfect habitat for deer ticks and the white-footed mice they parasitize. Major constituent chemicals include quinines (eg, anthraquinone, naphthoquinone, phylloquinone) and emodin-type anthroquinones, stilbenes (eg, resveratrol, piceatannol polydatin), flavonoids (eg, quercetin, catechin, rutin), coumarins, lignans, and other compounds.Chen 2012, Du 2013, Hao 2012, Kirino 2012, Li 2013, Peng 2013, Piotrowska 2012, Shen 2011, Zhang 2012, Emodin and phsycion demonstrate anti-inflammatory effects.Shen 2011 The stilbene content, including resveratrol, resveratroloside, polydatin, and piceatannol, are responsible for observed antioxidant activity.Kirino 2012, Piotrowska 2012, Methods of identification have been published, including high-performance liquid chromatography and thin-layer chromatography, which are based on the content of emodin and polydatin (minimum concentrations of 0.6% and 0.15%, respectively, per the Chinese pharmacopoeia). Hope this helps! It has blood-thinning properties. Quite a difference. The plant is native to eastern Asia, including Japan, China, and Korea. Andrographis herb – 430 mg. (Andrographis paniculata) – organic – India Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Most of the effects of Japanese Knotweed can be traced back to either the stilbenes (resveratrol) or the anthraquinones (emodin) for the circulatory and gastrointestinal help, respectively. This site uses Akismet to reduce spam. You may be aware that the herbicide, glyphosate is often used to remove Japanese knotweed. The male and female flowers occur on separate plants, and the fruits are black/brown, shiny, and ovoid. http://greendragonbotanicals.com/products/lyme-related-herbs/. Finally bought an ounce of loose, Japanese Knotweed powder after contracting Lyme over a year ago. turmeric, echinacea, saw palmetto, milk thistle, Ginkgo Biloba. Nature 410, 227–230 (2001). In people with certain genetic variations of this enzyme, taking resveratrol will cause them to feel toxic and ill. There’s no way for me to know for sure what’s going on, but I think it’s important to respect the body and what it’s telling you. (Page 214 2nd ed. The most important health benefits of Japanese knotweed include its ability to prevent and treat cognitive disorders, improve heart health, lower your risk of cancer, reduce gastrointestinal distress, lower blood pressure, maintain proper insulin levels, and many other unique benefits. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. my sister is pushing this for me to try as she is not responding to the doxycycline. To use Japanese Knotweed Root tincture for cancer treatment, you will need to work with a healthcare professional to determine a dosage relevant to your treatment plan. Hi Patty, We carry some standards and also hard to find tinctures. BioPure Japanese Knotweed from Polygonum cuspidatum, also known as Japanese Knotweed, or by the Mandarin Chinese name of Hu Zhang, is native to Asia, and is a robust perennial in the Buckwheat family. Like it was mentioned before, this plant … It has mucous hollow stems with reddish purple spots and ovate/elliptical deciduous leaves (5 to 12 cm by 4 to 9 cm). Medically reviewed by Drugs.com. Japanese Knotweed root – 500 mg. 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